WebSelf-immolative polymers (SIPs) are a unique type of mols. that respond to external stimuli by undergoing head-to-tail disassembly through a self-immolative fragmentation. We have demonstrated how these polymers can be applied as activity-linked labeling probes for … American Chemical Society WebApr 1, 2008 · We synthesized a self-immolative polymer that amplifies a single cleavage reaction into multiple release of fluorogenic molecules and confirmed the head-to-tail disassembly concept. These polymers can be used to prepare highly sensitive molecular sensors with large signal-to-noise ratios.
Controlled depolymerization: Stimuli-responsive self-immolative polymers
WebAug 9, 2024 · Self-Immolative Polymers: An Emerging Class of Degradable Materials with Distinct Disassembly Profiles. Journal of the American … Weba) Structure of the self-immolative polymers (SIP). SIP1 displays a capping group susceptible of cleavage in the presence of BSA (bovine serum albumin), whereas SIP2 contains a cap that responds to hydrogen peroxide (H 2 O 2).Both polymers are modified to be conjugated to silica (SiO 2) particles.b) Locomotion of motors containing SIP1 and SIP2. cooking a jacket potato in oven and microwave
The architectural evolution of self-immolative polymers
WebJul 19, 2024 · We have presented a responsive polymer consisting of a self-immolative backbone decorated with catechol units. Through catecholato–Al 3+ cross-links, the polymers form dual-responsive hydrogels in a pH-responsive fashion. Gel degradation and concomitant release of trapped cargo are triggered either by lowering pH and cleaving the … WebJun 1, 2015 · Self-immolative linear polymers are a recently developed class of materials that typically undergo head-to-tail depolymerization in response to the cleavage of stimuli-responsive end-caps from... WebMay 1, 2008 · A self-immolative polymer (SIP) is a macromolecule that is rapidly depolymerized into a small molecule through the domino-like cleavage of the backbone or terminal in a specific stimulus [23].... cooking a john morrell ham in a oven bag