Hepatocyte nuclear factor 4 alpha hnf4a
WebIntroduction. Maturity-onset diabetes of the young (MODY) is an autosomal dominant form of diabetes. 1 Heterozygous mutations in hepatocyte nuclear factor 1α (HNF1α) cause MODY subtype 3 (MODY3), which is one of the most common types. 1–3 HNF1α is a homeobox transcription factor expressed in pancreatic islets, liver, kidney and intestine. … Web1 jun. 2010 · To study whether the HNF4α binding site at the region −206/−167 is a functional binding site for nuclear proteins, EMSA was performed using nuclear extracts from SK-Hep1 cells. A −206/−167 oligonucleotide encompassing the putative HNF4α binding site at −202/−177 of the CTRP5 promoter forms a DNA–protein complex with SK …
Hepatocyte nuclear factor 4 alpha hnf4a
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Web28 feb. 2024 · Hepatocyte nuclear factor 4 alpha (HNF4A) was identified more than three decades ago as a liver-specific DNA binding activity in nuclear extracts. When its cDNA … WebCompare HNF 4 alpha (HNF4A) (NM_175914) Human Tagged ORF Clone Lentiviral Particle from OriGene Technologies on Biocompare.com. Welcome Guest. Sign In Register. ... NCBI Full Gene Name hepatocyte nuclear factor 4 alpha; NCBI Gene Aliases FRTS4, HNF4, HNF4a7, HNF4a8, HNF4a9, HNF4alpha, MODY, MODY1, NR2A1, NR2A21, …
Web21 mrt. 2024 · HNF4A (Hepatocyte Nuclear Factor 4 Alpha) is a Protein Coding gene. Diseases associated with HNF4A include Fanconi Renotubular Syndrome 4 With … Web14 nov. 2016 · HNF4A:hepatocyte nuclear factor 4 alpha [Gene - OMIM - HGNC] Variant type: single nucleotide variant Cytogenetic location: 20q13.12 Genomic location: Chr20: …
Web31 mrt. 2024 · Najmi LA, Aukrust I, Flannick J, Molnes J, Burtt N, Molven A, Groop L, Altshuler D, Johansson S, Bjorkhaug L, Njolstad PR. Functional Investigations of HNF1A … Web6 jul. 2024 · Hepatocyte nuclear factor 4 α (HNF4A) is a highly conserved nuclear receptor that has been associated with ulcerative colitis. In mice, HNF4A is …
WebNM_175914.5(HNF4A):c.427-5C>T AND not specified Clinical significance: Uncertain significance (Last evaluated: Apr 16, 2015) Review status: 1 star out of maximum of 4 stars
WebSuch increase has been supposed to be the result of 1) the increased glucagon secretion induced by the SGLT2 inhibition, and 2) the fact that alpha cells could express SGLT1/2 transporters. 47 However, experimental conditions cannot be compared: 1) a dual SGLT1/2 inhibitor was used in the present study while selective SGLT2 inhibitors were used in the … choc molten cakeWeb14 feb. 2024 · Hepatocyte nuclear factor 4 alpha (HNF4α) nuclear receptor is a master regulator of hepatocyte development, nutrient transport and metabolism. HNF4α is … graveyard keeper download torrentWeb1 jun. 2016 · Hepatocyte nuclear factor 4 alpha (HNF4A) also known as NR2A1 (Nuclear Receptor Subfamily 2, group A, member 1) is a member of the nuclear receptor (NR) … graveyard keeper cook multiple itemsWebDescription: Homo sapiens hepatocyte nuclear factor 4 alpha (HNF4A), transcript variant 7, mRNA. (from RefSeq NM_001258355) RefSeq Summary (NM_000457): The protein … graveyard keeper faceted diamondWeb27 apr. 2024 · HNF4A:hepatocyte nuclear factor 4 alpha [Gene - OMIM - HGNC] Variant type: single nucleotide variant Cytogenetic location: 20q13.12 Genomic location: Chr20: 44429627 (on Assembly GRCh38) Chr20: 43058267 (on Assembly GRCh37) Preferred name: NM_175914.5(HNF4A):c.1321A>G (p.Ile441Val) graveyard keeper faith farmingWeb1 aug. 2015 · Interestingly, the transcription factor HNF1A has been shown to be necessary for promoter activation of the DPP4 gene (14). Thus, patients with MODY3 may have altered DPP4 expression (and overall DPP4 enzymatic activity) and therefore potentially also altered levels of intact GLP1 and GIP after meal ingestion. graveyard keeper download pc gratischoc mortel