Fip200的表达
WebNov 23, 2024 · K562 wild-type (WT) and FIP200 KO cells expressing tf-NBR1 or tf-LC3 were nucleofected with TagBFP or TagBFP-FIP200 and analyzed for red:green ratio and BFP expression at 8 h post-nucleofection. Median values for each sample are identified by a black line within each violin. The red dotted line corresponds to the red:green ratio of … WebOct 19, 2016 · 在自噬溶酶体组装前自噬信号是通过由 ulk1 或 ulk2、fip200 和 matg13 组成的 ulk 复合物的活化介导的。 ULK1 复合物在体内是连接上游营养或能量感受器 mTOR 和 AMPK 与下游自噬体形成的桥梁。
Fip200的表达
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WebDec 13, 2024 · FIP200 is an essential autophagy gene implicated in the regulation of postnatal neural progenitor/stem cells (NSCs). However, the contribution of FIP200’s canonical-autophagy function and its ... WebMay 1, 2008 · FIP200 gene expression, protein structure and subcellular localization. FIP200 was initially identified as a Pyk2 interacting protein through yeast two-hybrid …
WebFIP200是一个多功能蛋白， FIP200-ULK1-ATG13复合物对自噬体的形成是必需的。. 活性氧会在FIP200缺失的胚胎造血干细胞的线粒体中积累，提示FIP200可能参与调控活性氧的 … WebNov 23, 2024 · K562 wild-type (WT) and FIP200 KO cells expressing tf-NBR1 or tf-LC3 were nucleofected with TagBFP or TagBFP-FIP200 and analyzed for red:green ratio and BFP …
WebApr 18, 2024 · FIP200 and SINTBAD/NAP1 are each recruited independently to bacteria via NDP52, as revealed by selective point mutations in their respective binding sites, but only in their combined presence does xenophagy proceed. Such recruitment of the upstream autophagy machinery by NDP52 reveals how detection of cargo-associated "eat me" … WebRecent studies have identified FIP200 as a crucial signaling component to coordinately regulate different cellular events by its interaction with multiple signaling pathways. This review will focus on the cellular functions of FIP200 and its interacting proteins, as well as the emerging roles of FIP200 in embryogenesis and cancer development.
WebOct 5, 2024 · fip200凝聚体通过与内质网膜蛋白vaps和atls结合，稳定定位于内质网上，并沿着内质网移动，与其他fip200凝聚体融合。 在达到一定大小后，FIP200凝聚体停止融 …
WebJan 14, 2013 · Chano et al. (2002) found that 7 of 35 (20%) primary breast cancers examined contained mutations in RB1CC1, including 9 large interstitial deletions predicted to yield markedly truncated RB1CC1 proteins. In all 7 cases, the RB1CC1 gene in the germline was wildtype; all deletions represented somatic mutations. Wildtype RB1CC1 and RB1 … cnn fear and greed index vs s\u0026p 500cnn fcc text message newsWebATG7 FIP200 舌鳞状细胞癌 氯喹. 1: 刘远辉;miRNA-20a靶向Atg7影响的自噬对造影剂诱导的急性肾损伤的机制研究及新的急性肾损伤危险因素探讨[D];南方医科大学;2016年 2: 班允 … cake the shampooWeb12421 Ensembl ENSG00000023287 ENSMUSG00000025907 UniProt Q8TDY2 Q9ESK9 RefSeq (mRNA) NM_001083617 NM_014781 NM_009826 RefSeq (protein) NP_001077086 NP_055596 NP_033956 Location (UCSC) Chr 8: 52.62 – 52.75 Mb Chr 1: 6.21 – 6.28 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse RB1-inducible coiled-coil … cnn fear greed cryptoWebJan 4, 2024 · FIP200 flox/flox mice, in which exons 4 and 5 are flanked by loxp sites, and progesterone receptor cre (PR cre/+) mice were previously described. Mice from the two lines were mated together to generate female mice with FIP200 conditionally ablated in the reproductive tract (FIP200 flox/flox PR cre/+ mice, hereafter referred to as FIP200 cKO). cnn fda boosterWebOct 22, 2024 · FIP200, also known as RB1CC1, is a protein that assembles the autophagy initiation complex. Its post-translational modifications and degradation mechanisms are unclear. Upon autophagy activation, we find that FIP200 is methylated at lysine1133 (K1133) by methyltransferase SETD2. We identify the E3 ligase Trim21 to be … cake thermometer temperaturehttp://sioc.cas.cn/xwzx/kyjz/202403/t20240316_5975166.html cake the show